To investigate the change of T lymphocyte and the subsets in gynecologic tumors, we measured the ratios of T lymphocyte, B lymphocyte and subsets(T4, T8 cells) in patient's peripheral blood by using flowcytometry.
In this study, the patients were included 16 benign gynecologic tumor, 110 malignancy and 15 control group.
@ES The results obstained were analysed as follows:
@EN 1. The ratios of T-cell, B-cell, T-cell, T8-cell and T4/T8 were 71.4±7.26, 15.5±6.16, 42.7±7.68, 32.6±8,48, and 1.4±0.47 respectively.
2. The ratios of T-cell, B-cell, T4-cell, T8-cell and T4/T8 were 66.9±8.49, 13.1±6.45, 37.9±7.89, and 1.3±09.52 respectively and there were no significant different ratios compared with normal control group.
3. There was no significant difference between lmphocyte ratios in 63 cases of pretherapeutic cervical cancer group and normal control group.
4. There was a significant decrement I T0cells in 6 cases of pretherapeutic malignant ovavian tumore compared with normal control group, but there was no signicatn difference in B-cells.
5. There was a significant difference in T-cells of malignant ovarian tumors after chemotherapy and operation compared with normal control group(P<0.05).
|